This is a 5 minutes explainer of the technical details of our latest published article: Kutuzova et al. “Taxometer: Improving taxonomic annotations of metagenome contigs”, Nature Communications. https://www.nature.com/articles/s41467-024-52771-y
More about hierarchical losses: https://youtu.be/NAiw8atLktk?si=KqdGIMyKxBHkRGGg
The software source code is at https://github.com/RasmussenLab/vamb
The animations are made with a fantastic Manim library https://www.manim.community/. All the code is here https://github.com/sgalkina/animations/blob/main/notebooks/Taxometer.ipynb
00:00 – Features: abundance vector
00:41 – Features: tetranucleotide frequency
01:05 – Neural network
01:45 – Hierarchical loss
03:26 – Workflow
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